ARTICLES

Zamore, P.D., Tuschl, T., Sharp, P.A., Bartel, D.P. (2000) RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101: 25-33. [MEDLINE]

Elbashir, S.M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., Tuschl, T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498. [MEDLINE]

Matzke MA, Birchler JA. (2005) RNAi-mediated pathways in the nucleus. Nat. Rev. Genet. 6: 24-35. [MEDLINE]

Huppi K, Martin SE, Caplen NJ. (2005) Defining and assaying RNAi in mammalian cells. Mol. Cell 17, 1-10. [MEDLINE]

Karagiannis TC, El-Osta A. (2004) siRNAs: Mechanism of RNA Interference, In Vivo and Potential Clinical Applications. Cancer Biol. Ther. 3, 1069-1074. [MEDLINE]

Shi Y. (2003) Mammalian RNAi for the masses. Trends Genet. 19, 9-12. [MEDLINE]